The ChromSep system combines simplicity with extraordinary flexibility and considerable savings on column and operating costs. The ChromSep 316 Stainless Steel column-housing hardware is a durable one-time investment. Once you have purchased the complete basic system of a holder, analytical cartridge and guard column, you will only need to replace the cartridges or replacement guard columns, both of which are available in economical packages; 3-pack analytical column replacements and 5-pack guard column replacements for added value.