The proprietary derivatisation procedure for YMCbasic allows YMC to produce a material with controlled surface coverage, which shows excellent lot-to-lot reproducibility as a result of closely monitoring both the production of the silica support and the bonding process.
The resulting YMCbasic material shows a different hydrophobicity compared with C8 or C18 phases.
Features:
alternative bonding approach to reduce peak tailing of basic pharmaceuticals
no need for ion pair reagents or amine modifiers
complementing selectivity to C8 and C18 materials
The recommended pH range for YMCbasic is 2-7,5. Remove acids and buffer salts before storage. Store the column in methanol/water=70/30. Clogged inlet frits often can be cleaned by changing the flow direction or replacement.