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ChromSword at ISC 2026: Advancing the Future of HPLC Method Development

September 08, 2026 Updated September 08, 2026
ISC is one of the leading international events dedicated to separation science, bringing together researchers, analytical scientists, instrument manufacturers, software developers, and industry experts from around the world. The 2026 program covers a broad range of chromatographic technologies and applications, including advances in column technology, multidimensional separations, bioanalysis, LC/MS, artificial intelligence and machine learning, automation, and the analysis of complex biomolecules. For ChromSword, ISC 2026 provides an excellent opportunity to demonstrate how automation, modelling, and intelligent data-driven approaches can transform HPLC method development.

ChromSword at ISC 2026: Advancing the Future of HPLC Method Development

ChromSword is pleased to participate in the 35th International Symposium on Chromatography (ISC 2026), taking place in Prague, Czech Republic, from September 6–10, 2026.

ISC is one of the leading international events dedicated to separation science, bringing together researchers, analytical scientists, instrument manufacturers, software developers, and industry experts from around the world. The 2026 program covers a broad range of chromatographic technologies and applications, including advances in column technology, multidimensional separations, bioanalysis, LC/MS, artificial intelligence and machine learning, automation, and the analysis of complex biomolecules.

For ChromSword, ISC 2026 provides an excellent opportunity to demonstrate how automation, modelling, and intelligent data-driven approaches can transform HPLC method development.

From trial-and-error to systematic method development

Developing a robust HPLC method can traditionally involve a considerable number of experimental runs, particularly when multiple chromatographic parameters need to be evaluated simultaneously. As analytical laboratories face increasing demands for efficiency, reproducibility, robustness, and regulatory compliance, a more systematic approach to method development is becoming increasingly important.

ChromSword's software solutions are designed to support this transition.

The ChromSword platform combines HPLC modelling, automated experimentation, optimization, robustness evaluation, and data analysis to help scientists develop chromatographic methods in a structured and knowledge-driven way. Its technologies are designed to reduce unnecessary experimentation while providing a deeper understanding of the relationship between chromatographic conditions and separation performance.

At ISC 2026, visitors can meet the ChromSword team at Booth 6 and see how automated method development can be incorporated into modern analytical workflows.

Intelligent automation for modern laboratories

A major theme of ISC 2026 is the growing role of artificial intelligence and machine learning in separation science. The symposium's scientific program specifically identifies AI and machine learning as an area of interest within chromatographic fundamentals, alongside automation and advanced separation technologies.

This development reflects a broader change in analytical laboratories. Modern method development increasingly relies not only on experimental expertise, but also on the ability to efficiently interpret experimental data, model chromatographic behaviour, identify optimal conditions, and understand method robustness.

ChromSword supports this approach through its automated HPLC method development technologies. ChromSwordAuto provides automated screening and optimization capabilities, while ChromSword Offline enables scientists to build retention models and simulate chromatographic separations before committing to additional laboratory experiments. The platform also includes tools for robustness assessment, reporting, scouting, and method development workflows.

Supporting the entire method development process

One of the key advantages of a systematic approach is that method development can be viewed as more than simply finding a set of chromatographic conditions that produces acceptable peaks.

A modern workflow can incorporate:

  • systematic screening of chromatographic conditions;
  • retention modelling and prediction;
  • automated method optimization;
  • evaluation of critical method parameters;
  • robustness testing and design of experiments;
  • definition of method operating regions and design spaces;
  • visualization and reporting of experimental results; and
  • support for method lifecycle management.

ChromSword's portfolio is designed to address these stages, including Developer, AutoRobust, ReportViewer, Offline, Scout, and ChromSwordAuto. The company also provides solutions for large-molecule method development, covering applications such as proteins, peptides, antibodies, DNA, and other complex molecules.

This broad approach reflects ChromSword's long-standing focus on integrating automation and scientific modelling into HPLC method development. The company has been developing software for liquid chromatography method development for more than 30 years and works with pharmaceutical and analytical laboratories internationally.

Meeting the chromatography community in Prague

ISC 2026 is not only an opportunity to showcase technology but also an opportunity for ChromSword to engage directly with the scientific community.

Conversations with chromatographers, analytical development scientists, pharmaceutical laboratories, researchers, and instrument manufacturers provide valuable insight into the challenges laboratories face today. These discussions help identify where automation and intelligent method development can provide the greatest practical benefit.

The timing is particularly relevant as analytical laboratories increasingly seek to combine scientific understanding with automation and digital tools, moving away from purely experience-based trial-and-error approaches.

Visit ChromSword at ISC 2026

ChromSword welcomes visitors to Booth 6 at ISC 2026 in Prague to discuss current challenges in HPLC method development and explore how automated modelling and optimization can support more efficient chromatographic workflows.

Whether developing methods for small molecules, pharmaceuticals, peptides, proteins, or other complex samples, ChromSword provides tools designed to help scientists move from experimental data to optimized and robust chromatographic methods more efficiently.

Visit ChromSword at Booth 6 and discover how intelligent automation can change the way HPLC methods are developed.

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