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Catalog Search results 00G-4445-V0-AX

00G-4445-V0-AX

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Clarity Oligo-RP

by Phenomenex

Purification and Analysis of Synthetic Oligonucleotides

The Clarity BioSolutions HPLC portfolio includes novel RP-HPLC and IEX-LC columns for purifiying and characterizing synthetic DNA / RNA used in biological research, therapuetic development, and biochemical manufacturing.

Clarity Oligo-MS™: LC/MS analysis
Clarity Oligo-RP™: RP-HPLC purification and analysis
Clarity Oligo-WAX™: IEX-LC purification

RP-HPLC Preparative Purification

Easily isolate target peak from N-1 / N+1 impurities to acheive >90 % purity of most synthetic oligonucleotides eliminating the need for extra purification steps.

3 µm, 5 µm, 10 µm particles for seamless scaling
Cut larger fractions due to baseline resolution
Increased loadability compared to ion exchange

Highly Selective RP-HPLC Analysis

Baseline separate DNA or RNA strands with slightly different sequences to resolve difficult synthetic mixtures for easier quantitation.

Analyze oligos up to 60mer
High pH (1-12) and temperature stability (80 °C)
Hydrophobic, dipoloar, pi-pi, hydrogen bonding of sorbent facilitates unique selectivity

Specification

Vendor	Phenomenex	Length
Brand	Clarity Oligo-RP	Internal Diameter
Mode	Reversed-Phase	Pore size	110
Particle Size

Similar columns from other manufacturers to Clarity Oligo-RP

Up to 10 unique Brand families from other Vendors with the same Mode and the same Modification.

How similarity is calculated

Eligible families receive a weighted score from Modification (25%), Product Usage (20%), Carbon Load (15%), Endcapping (10%), Pore Size (10%), Surface Area (8%), pH Stability (8%) and Particle Size (4%). The score uses data available in both families and requires at least three comparable criteria, at least 50% data coverage and a minimum 55% score. A relevant active sponsor may appear first and is always labelled Sponsored.

A similarity score does not guarantee identical selectivity or performance. Confirm suitability under the intended method conditions.

No other-Vendor Brand family with the same Mode and Modification meets the comparable-data and similarity thresholds.

Product Usage values

Oligonucleotides

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