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577309-U
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Ascentis ES-Cyano

by Sigma Aldrich

Ascentis® ES-Cyano HPLC Column
3 μm particle size, L × I.D. 10 cm × 2.1 mm             

Ascentis®
We have placed heavy emphasis on optimizing Ascentis phases with relation to the three terms of the resolution equation: efficiency, retention and selectivity. However, our strongest emphasis has been on the most powerful term, selectivity. Together, Ascentis bonded phases have a wide range of selectivities. It is likely that one or more Ascentis phase will accomplish any small molecule HPLC separation. Packed in micro- to preparative hardware dimensions, Ascentis products cover all HPLC application areas, including the most sensitive trace-level analyses.

Features and Benefits

  • Enhanced stability at low pH
  • Operates in reversed-phase, HILIC, and normal phase modes of chromatography
  • Low MS bleed
  • 100% aqueous compatible
  • Available as 3 μm and 5 μm particles
  • Particle composition: Type B silica gel
  • Particle shape: Spherical

Extra stable for low pH mobile phases due to sterically protected phase.

Useful for selectivity in the reversed-phase mode, including π π and dipole-dipole interacting compounds. Can also be used HILIC mode and normal phase chromatography.

Specification
Vendor Sigma Aldrich Pore size 100
Brand Ascentis ES-Cyano pH stability from 1.0
Modifification Silica/ Diisopropyl cyano propyl pH stability to 8.0
Mode Reversed-Phase Surface Area 450
Particle Size Carbon Load, % 10.0
Length Endcapped Yes
Internal Diameter Operating Temperature 70
Similar columns from other manufacturers to Ascentis ES-Cyano

Up to 10 unique Brand families from other Vendors with the same Mode and the same Modification.

How similarity is calculated
Eligible families receive a weighted score from Modification (25%), Product Usage (20%), Carbon Load (15%), Endcapping (10%), Pore Size (10%), Surface Area (8%), pH Stability (8%) and Particle Size (4%). The score uses data available in both families and requires at least three comparable criteria, at least 50% data coverage and a minimum 55% score. A relevant active sponsor may appear first and is always labelled Sponsored.
A similarity score does not guarantee identical selectivity or performance. Confirm suitability under the intended method conditions.
No other-Vendor Brand family with the same Mode and Modification meets the comparable-data and similarity thresholds.
Product Usage values
Pharmaceutical molecules
Application values
No Application values are assigned to this Product.
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