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Catalog Search results SH1-220.250.1030

SH1-220.250.1030

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SHARC 300

by SIELC

SHARC™ HPLC columns are the latest innovation from SIELC Technologies, the inventors of Primesep®. SHARC columns are the first commercially available columns with separation based primarily on hydrogen bonding. SHARC stands for Specific Hydrogen-bond Adsorption Resolution Chromatography.

Hydrogen bonding is an interaction between hydrogen atom bound to electronegative atoms in a molecule, such as oxygen, nitrogen, fluorine. This is typically a weak interaction, especially when separation is performed in aqueous solutions. Liquid chromatography techniques evolved as tool for separation of different molecules based on their physico-chemical properties. Most common techniques of the separation are:

Hydrophobic separation based on degree of hydrophobicity of the molecule
Ion-exchange separation based on number, nature, and distribution of charges in the molecule.
Normal phase separation based on hydrophilic properties of the molecules including molecule dipoles value and dipoles position
Size exclusion separation (SEC) based on molecule size and shape

Specification

Vendor	SIELC	Particle Size
Brand	SHARC 300	Length
Modifification	Hydrogen bond	Internal Diameter
Mode	Normal-Phase/Reversed-Phase/HIC/Size-Exclusion	Pore size	300

Similar columns from other manufacturers to SHARC 300

Up to 10 unique Brand families from other Vendors with the same Mode and the same Modification.

How similarity is calculated

Eligible families receive a weighted score from Modification (25%), Product Usage (20%), Carbon Load (15%), Endcapping (10%), Pore Size (10%), Surface Area (8%), pH Stability (8%) and Particle Size (4%). The score uses data available in both families and requires at least three comparable criteria, at least 50% data coverage and a minimum 55% score. A relevant active sponsor may appear first and is always labelled Sponsored.

A similarity score does not guarantee identical selectivity or performance. Confirm suitability under the intended method conditions.

No other-Vendor Brand family with the same Mode and Modification meets the comparable-data and similarity thresholds.

Product Usage values

Broad range of analytes Geometrical isomers Mixtures with differing retention Positional isomers

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