ChiroSil HPLC columns are especially designed for separating enantiomere solutions of various natural and unnatural α-amin acids, α-amin acid derivates and primary amines. These HPLC columns are also optimized for racematic composites amin alcoholics and secundary amines as well as drug realted primary and secundary amines.

One of the most significant advantages of ChiroSil towards other crown ether based columns is the possebility to use various mobile phases without decreasing chiral selectivity cause by covalent bounded chiral selectors. Furthermore ChiroSil stationary phases can be used with normal and reversed-phases solvents.