The Epitomize CSP-2 series, shown in the table below, is based on derivatized polysaccharides that are covalently-bound to silica gel. The covalent linkage permits the use of all typical organic solvents including ketones (e.g., acetone), halogenated solvents (e.g., dichloromethane and chloroform), ethyl acetate, THF, MTBE, and other aggressive solvents such as DMF and DMA. The CSP-2 series allows the separation of many new racemates that could not be accomplished on coated CSPs due to mobile phase limitations. The CSP-2-R series is available for aqueous-based mobile phases.