Pursuit PFP: For Dipole Based Polar Separations

• Unique fluorine based selectivity
• Powerful resolution of positional isomers and halogenated compounds
• High aqueous compatibility

The pentafluorophenyl ligand of Pursuit PFP provides an orthogonal separation mechanism to traditional reverse phase columns. By specifically targeting many polar retention mechanisms, Pursuit PFP can separate analytes based on small differences in structure, substitution, and steric access to polar moieties. The resulting selectivity for positional isomers, halogenated compounds, and polar analytes is particularly useful in the analysis of complex mixtures, and small molecule pharmaceuticals.

The 200Å pore structure of Pursuit PFP is particularly resistant to de-wetting phenomena or phase collapse. This, together with the polar retention mechanisms of PFP, allows the column to be used in high aqueous conditions, conditions ideal for the retention of highly polar analytes.