A2000250X040

Polaris C18-A and Polaris C8-A: For all Phases of Drug Development

• Universal stationary phases for maximum flexibility
• Ideal for polar acids, polar bases, and non-polar components
• High aqueous compatibility

Polaris C18-A and C8-A are polar modified phases specially designed for high throughput and LC/MS applications in drug discovery, drug metabolism, and analytical research and development. Based on 200Å ultra-pure silica, these polar modified phases are bonded with a polar group near the silica surface to deactivate residual silanols. The non-polar interaction from the C18 is supplemented by a unique polar modification, offering general polar selectivity and retention for polar compounds in addition to hydrophobic interactions. Polar modification also helps prevent phase collapse under the high aqueous mobile phaseconditions that are often required for polar retention.

Polaris C18-A

Polaris C18-A is the best starting place for separations where the benefits of polar modified columns are desired. The polar modifications of C18-A help it avoid poor peak shape and retention issues in low organic conditions.

Polaris C8-A

Polaris C8-A offers an alternative selectivity to standard C8 phases and has a lower hydrophobicity than Polaris C18-A, making it ideal for polar samples, or faster overall analysis times.