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57182

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CarboPac PA100

by Dionex

Oligosaccharides released from therapeutic glycoproteins can differ in size, charge, branching, and linkage. Oligosaccharides with these features can be resolved using the CarboPac® PA100. It provides the flexibility to separate oligosaccharides into broad classes depending upon the degree of sialylation, while maintaining the resolution needed for routine analysis based on linkage isomerism. Coupled with pulsed amperometric detection, the PA100 supports detection at low-picomole levels.

Separation of closely related oligosaccharides, even isomers, at picomole levels
Separation of neutral and charged oligosaccharides in the same run
No sample derivatization required for detection

The CarboPac PA100 column is a high-resolution, strong anion-exchange column for enhanced chromatography of oligosaccharides.

Specification

Vendor	Dionex	Internal Diameter
Brand	CarboPac PA100	Max Pressure	4000
Modifification	Quaternary ammonium	Operating Temperature	60
Mode	Anion-Exchange	pH stability from	0.0
Particle Size		pH stability to	14.0
Length

Similar columns from other manufacturers to CarboPac PA100

Up to 10 unique Brand families from other Vendors with the same Mode and the same Modification.

How similarity is calculated

Eligible families receive a weighted score from Modification (25%), Product Usage (20%), Carbon Load (15%), Endcapping (10%), Pore Size (10%), Surface Area (8%), pH Stability (8%) and Particle Size (4%). The score uses data available in both families and requires at least three comparable criteria, at least 50% data coverage and a minimum 55% score. A relevant active sponsor may appear first and is always labelled Sponsored.

A similarity score does not guarantee identical selectivity or performance. Confirm suitability under the intended method conditions.

No other-Vendor Brand family with the same Mode and Modification meets the comparable-data and similarity thresholds.

Product Usage values

Carbohydrate Oligosaccharides

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