760800.2

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

• totally spherical particle shape
• outstanding surface microstructure
• high pressure stability
• low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® Sphinx RP - High purity silica phase for HPLC
Bifunctional RP phase, balanced ratio of propylphenyl and C18 ligands
endcapped · 15 % C · USP L1 / L11

Properties
Key features:

• Distinct selectivity based on well-balanced bifunctional surface coverage
• Widens the scope for method development based on additional π-π interactions
• Suitable for LC/MS due to low bleeding characteristics

Technical characteristics:
Octadecyl and propylphenyl modified silica
pore size 110 Å; particle sizes 1.8 μm, 3 μm and 5 μm
carbon content 15 %; pH stability 1–10;
high reproducibility and consistent quality
 Recommended application:
Quinolone antibiotics, sulfonamides, xanthines, substituted aromatics