760149.4

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

• totally spherical particle shape
• outstanding surface microstructure
• high pressure stability
• low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® CN / CN-RP
High purity silica phase for HPLC
Cyano (nitrile) modification for NP and RP separations · 7 % C · USP L10

Features
 Key features:

• High retention capacity especially for very polar and unsaturated compounds
• Multi-mode column (RP and NP) widens scope of selectivity
• Stable against hydrolysis at low pH (working range pH 1-8)

Technical characteristics:
Cyanopropyl modified high purity silica; pore size 110 Å, particle sizes 3 µm and 5 µm; 7 % C; special endcapping
High reproducibility from lot to lot; different retention characteristics in comparison to C8 and C18
 Recommended application:
Tricyclic antidepressants, steroids, organic acids