XSelect™ HPLC columns are the next evolutionary step in Waters LC column technology. Based on Charged Surface Hybrid (CSH™) Technology, this HPLC column family offers the widest range of selectivity choices and superior peak shape improvements for basic compounds when operated in acidic, low ionic strength mobile phases (e.g., 0.1% formic acid).   XSelect OBD™ Prep columns offer extremely high mass loading under low ionic strength acidic conditions and raise the performance bar for lab-scale isolation and purification columns.

Responding to input received at many customer forums, Waters has developed the next evolution of particle technology: Charged Surface Hybrid (CSH^TM) Technology.

Advantages of CSH Technology include:

• Superior peak shape for basic compounds
• Increased loading capacity
• Rapid column equilibration after changing mobile-phase pH
• Improved batch-to-batch reproducibility
• Excellent stability at low pH

XSelect CSH C18 columns can be used as general purpose columns that provide alternative selectivity compared to other C18 sorbents. Charged Surface Hybrid (CSH) technology helps you overcome column related problems such as peak shape asymmetry and poor loading for basic compounds, column bleed, and slow mobile-phase re-equilibration.