YMC Chiral Prep CD is a cyclic malto-oligosaccharide, consisting of seven a-D-glucopyranose units linked through a-(1,4)-linkages (b-cyclodextrin), covalently bonded to YMC's high-purity silica gel.
YMC Chiral Prep CD is available in two versions with different selectivities: The unmodified standard (ST) version is suitable for reversed phase applications whilst the phenyl modified (PM) version can be used under both normal and reversed phase conditions.
The unique characteristics of b-cyclodextrin provide excellent stereospecific selectivity for the separation of enantiomers (mirror-image or optical isomers). The active chiral moiety, b-cyclodextrin, has a toroidal structure with a hydrophobic cavity formed with the glucoside oxygens and carbon backbones of the sugar residues, while a hydrophilic surface is formed with the primary and secondary hydroxy groups.
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