NUCLEODUR HILIC

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

• totally spherical particle shape
• outstanding surface microstructure
• high pressure stability
• low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® HILIC
High purity silica phase for Hydrophilic Interaction LIquid Chromatography

Properties
 Key features:

• Ideal for reproducible and stable chromatography of highly polar analytes
• Suitable for analytical and preparative applications as well as LC-MS
• Very short column conditioning period  

Technical characteristics:
Ammonium – sulfonic acid modified silica: pore size 110 Å, available particle sizes 1.8 µm, 3 µm and 5 µm; carbon content 7 %;
pH stability 2–8.5
 Recommended application:
Hydrophilic compounds such as organic polar acids and bases, polar natural compounds, nucleosides, oligonucleotides, amino acids, peptides, water soluble vitamins