NUCLEOSIL CN

NUCLEOSIL® standard silica phases for HPLC

Features

NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure

• Wide acceptance as routine packings for very different fields of chromatography
• One of the first spherical silicas used in HPLC
• Developed in the early seventies, it became a world-renowned HPLC packing
• Still found in many analytical and preparative applications
• An absolutely reliable choice in HPLC
• The largest variety of modified HPLC silicas available on the market

NUCLEOSIL® CN / CN-RP - Cyano (nitrile) modified silica phases for HPLC

Features

• Polar to mid-polar cyano (nitrile) modified silica for reversed phase and normal phase chromatography:
• Normal phase: with low-polarity solvents for many compounds, which can also be separated on unmodified silica, however, due to the rapid equilibration much more suitable for gradient separations
• Reversed phase: with different selectivity than C18, C8 or phenyl modified packings
• Available pore sizes 100, 120, 300 and 500 Å, available particle sizes 5 µm, 7 µm and 10 µm,
• pH stability at 20 °C: 2–8; carbon content 5 % for 100 Å pores, ~ 3 % for 120 Å pores
• Separation mechanism based on π–π interactions, polar interactions and hydrophobic interactions