NUCLEOSIL C18

NUCLEOSIL® standard silica phases for HPLC

NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure 

• Wide acceptance as routine packings for very different fields of chromatography
• One of the first spherical silicas used in HPLC
• Developed in the early seventies, it became a world-renowned HPLC packing
• Still found in many analytical and preparative applications
• An absolutely reliable choice in HPLC
• The largest variety of modified HPLC silicas available on the market

NUCLEOSIL® standard C18 phases - Octadecyl modified silica phases for HPLC

Features:

• Nonpolar, endcapped phases for RP chromatography
• Available pore sizes 50, 100, 120, 300, 500, 1000 and 4000 Å
• Available particle sizes 3 µm, 5 µm, 7 µm and 10 µm
• pH stability at 20 °C: 2–8, carbon content depending on pore size (see table below)
• Separation mechanism based on hydrophobic (van der Waals) interactions, slight residual silanol interactions