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Scherzo SM-C18

by Imtakt

Imtakt has developed a revolutionary multi-mode ODS column.

Many biomaterials / metabolites are ionic and cannot be retained on conventional ODS columns. Recent solutions for this issue have the following limitations:
* Ion-pairing RP chromatography is not compatible with LC-MS
* Aqueous NP (HILIC) fails to separate polar & non-polar compounds
 
Scherzo SM-C18 can solve many of these problems. SM-C18 contains ODS+cation+anion ligands and can be used to separate highly polar compounds. Unlike other mixed-mode RP columns, Scherzo SM-C18 contains ODS ligands, and shows similar behavior to conventional ODS columns for non-ionic compounds. In addition, the IEX ligands on SM-C18 are highly polar and provide normal phase mode. This allows for both RP + NP separation mode. This next generation (multi-mode) ODS column expands the separation possibilities for the ODS phase.
Specification
Vendor Imtakt Pore size 130
Brand Scherzo SM-C18 Max Pressure 3626
Modifification Silica/C18+WAX+WCX Surface Area 300
Mode Reversed-Phase+AX+CX Endcapped Yes
Particle Size Operating Temperature 65
Length pH stability from 1.5
Internal Diameter pH stability to 8.0
Similar columns from other manufacturers to Scherzo SM-C18

Up to 10 unique Brand families from other Vendors with the same Mode and the same Modification.

How similarity is calculated
Eligible families receive a weighted score from Modification (25%), Product Usage (20%), Carbon Load (15%), Endcapping (10%), Pore Size (10%), Surface Area (8%), pH Stability (8%) and Particle Size (4%). The score uses data available in both families and requires at least three comparable criteria, at least 50% data coverage and a minimum 55% score. A relevant active sponsor may appear first and is always labelled Sponsored.
A similarity score does not guarantee identical selectivity or performance. Confirm suitability under the intended method conditions.
No other-Vendor Brand family with the same Mode and Modification meets the comparable-data and similarity thresholds.
Product Usage values
Polar compounds
Application values
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