ZirChrom®-SHAX columns offer today's chromatographer the following advantages:

• Efficient strong anion-exchanger useful for inorganic and organic anions. Stable from pH 1-12.
• Hydrophilic surface useful for the separation of bio-molecules such as nucleotides, nucleosides, oligonucleotides, oligodeonucleotides, amino acids, peptides and proteins.
• High anion-exchange capacity that can be controlled by the amount of polymer deposited on the porous zirconia substrate.
• Different selectivity than silica, polymeric or ZirChrom-WAX anion-exchangers.
• Does not shrink or swell as a function of anionic strength or organic modifier content of the mobile phase.
• Extremely stable amino phase for normal phase separation of carbohydrates.
• Thermally stable up to 80^oC, which causes different selectivity and high speed separations with lower ionic strength mobile phases. This is very important in the preparation of RNA and DNA samples used for further studies.
• Mixed-mode separation modes may be exploited to optimize separations, including Lewis acid-base interactions, hydrophobic interactions and ion-exchange interactions. These modes may be attenuated by adjusting the strong Lewis base content, organic content and ionic strength of the mobile phase, respectively.