NUCLEOSIL® standard silica phases for HPLC

Features

NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure

• Wide acceptance as routine packings for very different fields of chromatography
• One of the first spherical silicas used in HPLC
• Developed in the early seventies, it became a world-renowned HPLC packing
• Still found in many analytical and preparative applications
• An absolutely reliable choice in HPLC
• The largest variety of modified HPLC silicas available on the market
   

NUCLEOSIL® C4 - Butyl modified silica phases for HPLC
Medium density modification, endcapping · ~ 2 % C · USP L26

Features

Endcapped phases for RP and ion-pairing chromatography
Available pore sizes 120, 300, 500, 1000 and 4000 Å, available particle sizes 5 µm, 7 µm and 10 µm
Separation mechanism based on hydrophobic (van der Waals) interactions, some residual silanol interactions
Retention times are shorter than on C8 and C18 phases
pH stability at 20 °C: 2–8